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Your Treatment
What Can I Expect Before, During and After the Treatment?
Treatment Preparation
On the day prior to the procedure, you will be seen by the urologist,
the anesthesiologist, and the nurse. All your information will
have been reviewed in advance; however, you will have an opportunity
to ask any final questions.
To prepare the lower bowel for the procedure you will be provided
with an enema which is to be administered in the morning before
coming to the hospital for treatment.
Treatment Procedure
Since it is necessary that all your movement be minimized during
the treatment, spinal anesthesia is administered as well as intravenous
sedation so you will rest comfortably during the procedure. The
treatment may last anywhere from 2 to 3 hours depending on the
size of your prostate. The treatment is performed with you lying
on your right-hand side.
The urologist inserts a small probe into the rectum after coating
it with gel and placing it inside a latex balloon filled with
a cooling liquid. This maintains a constant temperature in the
rectal wall during the entire treatment. The urologist locates
the limits of the prostate by ultrasound examination and outlines
the zone he wishes to treat. Then 400 to 600 pulses of high-intensity
focused ultrasound are administered to the prostate. As a result
of the treatment the prostate swells immediately and compresses
the urethra. For this reason, a temporary catheter is inserted
into the bladder to drain urine until the swelling of the prostate
goes down. Generally, the catheter will be required to stay in
place for 14 days.
If you have an enlarged prostate with symptoms or signs of prostatic
obstruction (i.e. weak urinary stream, frequent urination at
night, or sensation of residual urine volume in the bladder),
you may need to have the prostate reduced prior to treatment.
This is usually done by the use of medication (cyto-reduction)
or by having part of your prostate resected prior to having the
treatment. This procedure is called a transurethral resection
of the prostate (TUR-P).
Immediate Post Treatment
As this is an ambulatory procedure, you will go to your hotel
the same day and be able to resume a normal diet the same evening.
The urinary catheter is generally removed 14 days after the treatment
date. You will need to take antibiotics while you have the catheter
in place to prevent the occurrence of a urinary infection. You
will notice white particles passing in the urine which is the
destroyed prostate tissue. You will also notice blood in the
urine at approximately day 7. This is part of the normal healing
process as more tissue continues to slough away. After the catheter
is removed, you may experience some mild burning and bleeding
when you start to void. Initially you may also experience more
frequent and sometimes a more urgent need to void. During the
healing process, you may experience some urine leakage on exertion
or if you do not get to the toilet on a timely basis. A urinary
tract infection with a fever is rare but possible. If a fever
develops you should contact your physician immediately.
How Many Treatments Will I Require?
Peer reviewed Journal Articles from Europe report on patients
treated as far back as 1995. Their re-treatment rate is approximately
10%. To date fewer than 3% of the patients treated in Toronto,
Ontario, Canada have required re-treatment. Indication for re-treatment
is if the PSA remains elevated after treatment or the PSA exceeds
ASTRO targets after achieving nadir levels. The ASTRO criteria
of failure is based upon the PSA value rising by more than 0.3
ng/ml in two successive 3 month periods or exceeding the nadir
value by more than 2.0 ng/ml. If this occurs a repeat trans rectal
ultrasound with biopsy would be required to determine if re-treatment
is necessary. A negative bone scan and abdominal and pelvic Cat
Scan would also be necessary. If a nerve sparing procedure is
done, the re-treatment rate may be higher. One unique advantage
of treatment with Ablatherm ® HIFU is the fact that re-treatment
is possible if tumor persists or recurs locally.
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