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Read the latest clinical data and comparison of HIFU
by John C. Rewcastle, Ph.D.,
University of Calgary

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Home » Patients » Ablatherm vs. HIFU: Key Differences

Ablatherm vs Sonablate (Page 3 of 8)

Key Differences Between Ablatherm® HIFU & Sonablate® 500

 
Ablatherm®
Sonablate ® 500
TURP required?
(A TURP is a surgical
procedure with some risk
of complications.)
 
At Maple Leaf HIFU, fewer than 2% of patients have required a TUR-P prior to Ablatherm HIFU. Willing to treat larger prostates but frequently require TURP post treatment or prolonged catheterization.
Image Quality Dual US Transducers in treatment probe provides superior 7.5 MHZ imaging while allowing optimum High Intensity Shock Wave Production with separate generator. Single 4.0 MHZ transducer compromises image quality
and treatment results.
Nerve Detection Superior imaging allows precise visualization and localization of neurovascular bundles allowing improved nerve sparing. No data available on preservation of erectile function with suboptimal visualization of 4.0 MHZ probe.
Energy Control Computer controlled. Auto detection of possible danger to rectum allows uniform application of energy level to effectively treat prostate. Requires physician input to reduce power and, in some cases, this could result in a failure to completely treat prostate tissue.
The Probe After initially positioned by physician, probe is fine tuned by robotic control and image recognition software to ensure accurate treatment. Allows very accurate delivery of energy to tolerance of 0.1 mm. Fully automated. Probe must be manually placed and manipulated. Very operator dependent.
Power Adjustment Three scientifically tested and optimal energy levels for de novo, radiation failure or HIFU retreatment conditions. Must vary energy based on visual clues to avoid periprostatic tissue injury. Significant risk of rectal injury.
Precision Variable height of focal
area in single probe allows energy to be delivered in pattern conformed to prostate anatomy
Probe geometry poorly configures to prostate anatomy.
Safety Features Four safety features including external motion detector, rectal wall temperature monitoring, rectal wall thickness and “probe to rectal wall” distance protect against rectal or preprostatic tissue injury. Automatic disengagement of firing device if parameters are violated. Image guided robotic fine tuning of probe position to ensure effective treatment. Safety devices require constant operator attention to monitor limited safety parameters and adjust device energy output to prevent rectal injury (fistula) or injury to surrounding tissue.
Treatment Time Integrated imaging with single probe and automated control keep treatment time under 2 hours in the majority of cases. Poor image quality and small treatment field extend treatment time up to 8 hours with an average treatment time of 2.8 hours.


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